How does 4DryField® PH work?


4DryField® PH is simply sprayed onto the wound area intraoperatively. This is also easy to do endoscopically, thanks to the excellent free-flowing properties of the 4DryField® PH powder. The fine white microparticles are easily visible as they stick to the tissue.

When combined with physiological saline solution, a viscous gelatinous coating forms within seconds. This creates a mechanical barrier that separates the corresponding wound areas. This temporary protection persists for long enough to facilitate peritoneal healing and thereby minimise the formation of fibrinous connections between the boundary layers.

Due to its molecular structure and the large surface area of its microparticles, 4DryField® PH extracts the liquid from the blood that leaks from the wound. Cellular blood components (erythrocytes, thrombocytes) and coagulation factors (fibrinogen, thrombin) are concentrated, which can accelerate the coagulation. The 4DryField® PH and blood form a coagulum as a barrier against further bleeding. Even with a 50% dilution of the blood, the coagulum induced by 4DryField® PH still shows excellent stability.

Over the course of several days, 4DryField® PH is broken down by the body’s own amylases and fully absorbed.


Adhesion prevention plus haemostasis in one medical device

 

  Adhesion prevention


Arrest of bleeding / haemostasis


How it works Due to the molecular structure of 4DryField® PH, when liquid is absorbed (physiological saline solution), the microparticles form a gel that creates a temporary mechanical barrier against the formation of adhesions.


By absorbing liquid from the blood, 4DryField® PH causes a concentration of the patient’s own coagulation factors resulting in accelerated coagulation.


Indication 4DryField® PH is indicated when the formation of postoperative adhesions needs to be prevented following surgery in cavities with a mesothelial lining (e.g. pericardium, chest cavity, abdominal cavity). 4DryField® PH is indicated in cases of surgical intervention or injury when the control of bleeding from arterioles, capillaries or veins is not effective or not practicable by means of conventional measures.